TRPA1: a potential target for anti-tussive therapy.

Abstract

Cough occurs as a result of the activation of specific airway sensory nerves. The mechanisms by which tussive stimuli activate these sensory nerves are starting to be understood and suggest that TRPA1 channels are heavily involved. TRPA1 channels are nociceptor-specific ion channels that are gated by a wide range of exogenous irritants and endogenously… (More)
DOI: 10.1016/j.pupt.2008.12.019

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