TRP expression pattern and the functional importance of TRPC3 in primary human T-cells.

@article{Wenning2011TRPEP,
  title={TRP expression pattern and the functional importance of TRPC3 in primary human T-cells.},
  author={Anna S Wenning and Katherina Neblung and Bettina Strauss and Melodie-Jo Wolfs and Anne Sappok and Markus Hoth and Eva C Schwarz},
  journal={Biochimica et biophysica acta},
  year={2011},
  volume={1813 3},
  pages={412-23}
}
TRP proteins form ion channels which are activated following receptor stimulation. In T-cell lines, expression data of TRP proteins have been published. However, almost no data about TRP expression is available in primary human T-cells. Using RT-PCR and quantitative RT-PCR, we compare the expression of TRP mRNA in 1) human peripheral blood lymphocytes, which are a mix of mostly mono-nuclear blood lymphocytes but contain other leucocytes, 2) a pure human CD4+ T-helper cell population in the… CONTINUE READING

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