TRP channels in schistosomes

@inproceedings{Bais2016TRPCI,
  title={TRP channels in schistosomes},
  author={Swarna Bais and Robert M Greenberg},
  booktitle={International journal for parasitology. Drugs and drug resistance},
  year={2016}
}
Praziquantel (PZQ) is effectively the only drug currently available for treatment and control of schistosomiasis, a disease affecting hundreds of millions of people worldwide. Many anthelmintics, likely including PZQ, target ion channels, membrane protein complexes essential for normal functioning of the neuromusculature and other tissues. Despite this fact, only a few classes of parasitic helminth ion channels have been assessed for their pharmacological properties or for their roles in… CONTINUE READING
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