TRP channels: potential drug target for neuropathic pain

@article{Marwaha2016TRPCP,
  title={TRP channels: potential drug target for neuropathic pain},
  author={Lovish Marwaha and Yashika Bansal and Raghunath Singh and Priyanka Saroj and Ranjana Bhandari and Anurag Kuhad},
  journal={Inflammopharmacology},
  year={2016},
  volume={24},
  pages={305-317}
}
Neuropathic pain is a debilitating disease which affects central as well as peripheral nervous system. Transient receptor potential (TRP) channels are ligand-gated ion channels that detect physical and chemical stimuli and promote painful sensations via nociceptor activation. TRP channels have physiological role in the mechanisms controlling several physiological responses like temperature and mechanical sensations, response to painful stimuli, taste, and pheromones. TRP channel family involves… CONTINUE READING