TRP Channels in Drug Discovery

@inproceedings{Szallasi2012TRPCI,
  title={TRP Channels in Drug Discovery},
  author={Arpad Szallasi and Tam{\'a}s B{\'i}r{\'o}},
  booktitle={Methods in Pharmacology and Toxicology},
  year={2012}
}
This introduction lists TRP channels as possible pharmaceutical targets and will also refer to some methodological and still scienti fi c caveats. First, it will be highlighted which scienti fi c problems are still necessary to solve, including permeation, gating regulation. This part leads to the methodological aspect of the book. Second, the well-known problem of evaluating expression of several TRP channels in organs which need to be affected will be shortly discussed. Third, natural… CONTINUE READING
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