TRH site-specific methylation in oral and oropharyngeal squamous cell carcinoma

  title={TRH site-specific methylation in oral and oropharyngeal squamous cell carcinoma},
  author={Charoenchai Puttipanyalears and Areeya Arayataweegool and Kanwalat Chalertpet and P. Rattanachayoto and Patnarin Mahattanasakul and Napadon Tangjaturonsasme and Veerachai Kerekhanjanarong and Apiwat Mutirangura and Nakarin Kitkumthorn},
  journal={BMC Cancer},
BackgroundThe incidence of oral squamous cell carcinoma (OSCC) continues to increase each year. Clinical examination and biopsy usually detect OSCC at an advanced stage that is difficult to treat, leading to poor prognosis. DNA methylation pattern is tissue specific and has emerged as a biomarker for the detection of cancers of tissue origin. Herein, we aimed to discover a novel site-specific methylation marker for OSCC.MethodsWe selected OSCC datasets analyzed using the… 
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