TRANSCRANIAL MAGNETIC STIMULATION (TMS) FOR MAJOR DEPRESSION: A MULTISITE, NATURALISTIC, OBSERVATIONAL STUDY OF ACUTE TREATMENT OUTCOMES IN CLINICAL PRACTICE

@article{Carpenter2012TRANSCRANIALMS,
  title={TRANSCRANIAL MAGNETIC STIMULATION (TMS) FOR MAJOR DEPRESSION: A MULTISITE, NATURALISTIC, OBSERVATIONAL STUDY OF ACUTE TREATMENT OUTCOMES IN CLINICAL PRACTICE},
  author={Linda L. Carpenter and Philip G. Janicak and Scott T. Aaronson and Terrence Boyadjis and David G. Brock and Ian A Cook and David L. Dunner and Karl Lanocha and Hugh Brent Solvason and Mark A Demitrack},
  journal={Depression and Anxiety},
  year={2012},
  volume={29}
}
Few studies have examined the effectiveness of transcranial magnetic stimulation (TMS) in real‐world clinical practice settings. 
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TLDR
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References

SHOWING 1-10 OF 43 REFERENCES
Has repetitive transcranial magnetic stimulation (rTMS) treatment for depression improved? A systematic review and meta‐analysis comparing the recent vs. the earlier rTMS studies
Objective:  To investigate whether the recent repetitive transcranial magnetic stimulation (rTMS) studies on depression using new parameters of stimulation have shown improved clinical results.
Efficacy of repetitive transcranial magnetic stimulation in depression: A review of the evidence
TLDR
There is insufficient evidence for rTMS as a valid treatment for depression at present, and Comparisons with electroconvulsive therapy (ECT) indicated the superiority of ECT.
Transcranial Magnetic Stimulation in the Management of Mood Disorders
TLDR
TMS appears to be an effective treatment; however, at 4 weeks’ follow-up after TMS, there had been no further change in depression severity, and only further large double-blind randomized controlled designs with systematic exploration of treatment and patient parameters will help to define optimum treatment indications and regimen.
Improving the antidepressant efficacy of transcranial magnetic stimulation: maximizing the number of stimulations and treatment location in treatment‐resistant depression
TLDR
The total number of rTMS stimulations needed to achieve remission in TRD may be higher than is used in most studies.
Repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and meta-analysis.
TLDR
For MDD patients with 2 or more antidepressant treatment failures, rTMS is a reasonable, effective consideration and how long these benefits persist remains unclear.
Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis.
Transcranial magnetic stimulation (TMS) is a technology that allows for non-invasive modulation of the excitability and function of discrete brain cortical areas. TMS uses alternating magnetic fields
Transcranial magnetic stimulation for depression and other psychiatric disorders
TLDR
Repetitive transcranial magnetic stimulation has demonstrable beneficial effects in depression and there now needs to be randomized controlled trials to compare rTMS directly with standardized electroconvulsive therapy in order to take this subject forward.
Transcranial magnetic stimulation in the acute treatment of major depressive disorder: clinical response in an open-label extension trial.
TLDR
This open-label study provides further evidence that TMS is a safe and effective treatment of major depressive disorder and provided additional benefit to some patients who failed to respond to 4 weeks of treatment, suggesting that longer courses of treatment may confer additional therapeutic benefit.
Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression: A Systematic Review and Metaanalysis
TLDR
RTMS appears to provide significant benefits in short-term treatment studies, however, the relatively low response and remission rates, the short durations of treatment, and the relative lack of systematic follow-up studies suggest that further studies are needed before rTMS can be considered as a first-line monotherapy treatment for TRD.
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