TRAIL-induced apoptosis of thyroid cancer cells: potential for therapeutic intervention


To determine whether the apoptotic machinery of thyroid cancer cells is functional and could be activated for tumoricidal purposes, we examined the apoptosis induced by the cytokines TNF-α, Fas and TRAIL in thyroid cancer cell lines, NPA and SW579. Interestingly, out of these cytokines, only TRAIL was able to trigger significant apoptosis. The tumoricidal… (More)
DOI: 10.1038/sj.onc.1203679

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