TRAIL and anti-tumor responses.

@article{Bhojani2003TRAILAA,
  title={TRAIL and anti-tumor responses.},
  author={Mahaveer Swaroop Bhojani and Brian D Ross{\'u} and Alnawaz Rehemtulla},
  journal={Cancer biology & therapy},
  year={2003},
  volume={2 4 Suppl 1},
  pages={S71-8}
}
The therapeutic use of TRAIL as an inducer of tumor specific cell death prove to be an useful strategy to overcome resistant of cancer cells to conventional chemotherapeutic agents. Although five death receptors have been identified which bind TRAIL and a number of checkpoint involved in TRAIL pathway are known, the molecular mechanism underlying the resistant or sensitivity of normal/transformed cells remains poorly understood. The key to the clinical use of TRAIL is that normal cells are… CONTINUE READING

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