TRAF molecules in cell signaling and in human diseases

@inproceedings{Wang2013TRAFMI,
  title={TRAF molecules in cell signaling and in human diseases},
  author={Zhanfeng Wang},
  booktitle={Journal of molecular signaling},
  year={2013}
}
The tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) family of intracellular proteins were originally identified as signaling adaptors that bind directly to the cytoplasmic regions of receptors of the TNF-R superfamily. The past decade has witnessed rapid expansion of receptor families identified to employ TRAFs for signaling. These include Toll-like receptors (TLRs), NOD-like receptors (NLRs), RIG-I-like receptors (RLRs), T cell receptor, IL-1 receptor family, IL-17 receptors… CONTINUE READING
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