TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3

@inproceedings{Chang2017TRADDMT,
  title={TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3},
  author={Xixi Chang and Li-li Wang and Zicheng Wang and Shuai Wu and Xiao-Ming Zhu and Shiping Hu and Yu Wang and Ji Yun Yu and Guozhu Chen},
  booktitle={Scientific Reports},
  year={2017}
}
Receptor-interacting protein kinase 3 (RIP3) is a critical initiator in mediating necroptosis induced by tumor necrosis factor alpha (TNFα) in L929 cells, so knockdown of RIP3 inhibits TNFα-induced L929 cell necroptosis. However, RIP3 knockdown was shown to switch TNFα-induced necroptosis to apoptosis in L929 cells in other studies. Therefore, whether RIP3… CONTINUE READING