TRACHOMA

@article{Solomon2022TRACHOMA,
  title={TRACHOMA},
  author={Anthony W Solomon and Matthew J. Burton and Emily W. Gower and Emma Michele Harding-Esch and Catherine E. Oldenburg and Hugh R. Taylor and Lamine Traoré},
  journal={Medical Journal of Australia},
  year={2022},
  volume={1}
}
Trachoma is a neglected tropical disease caused by infection with conjunctival strains of Chlamydia trachomatis. It can result in blindness. Pathophysiologically, trachoma is a disease complex composed of two linked chronic processes: a recurrent, generally subclinical infectious–inflammatory disease that mostly affects children, and a non-communicable, cicatricial and, owing to trichiasis, eventually blinding disease that supervenes in some individuals later in life. At least 150 infection… 
1 Citations

Global trends in Trachoma

TLDR
The USA and England are the leading countries in scientific production on this topic and the number of articles has never dropped under 100 articles per year since 1985.

References

SHOWING 1-10 OF 368 REFERENCES

Epidemiology and control of trachoma: systematic review

TLDR
There remain a large number of people with trichiasis who are at risk of blindness, and the WHO promotes trachoma control through a multifaceted approach involving surgery, mass antibiotic distribution, encouraging facial cleanliness and environmental improvements.

Trachoma: new assault on an ancient disease

  • S. West
  • Medicine
    Progress in Retinal and Eye Research
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Correlation of Clinical Trachoma and Infection in Aboriginal Communities

TLDR
In low prevalence areas, the LPS-based POC test lacks the sensitivity to detect active ocular infection and nucleic acid amplification tests such as PCR or the 16S-RNA based NAAT performed better.

Trachoma

Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

TLDR
An increasing number of studies indicate that innate immune responses arising from the epithelium and other innate immune cells, along with changes in matrix metalloproteinase activity, are important in the development of tissue damage and scarring.

Trachoma and Yaws: Common Ground?

TLDR
The extent to which the epidemiologies of and management strategies for these diseases actually overlap is reviewed, to determine areas for mutually beneficial collaboration.

The epidemiology of trachoma in central Tanzania.

TLDR
Clear evidence of clustering of trachoma by village, and within village, by neighbourhood, and by neighbourhood was found, and persisted even after accounting for differences in distance to water, local religion, and proportion of children with unclean faces.

Low Prevalence of Ocular Chlamydia trachomatis Infection and Active Trachoma in the Western Division of Fiji

TLDR
The study data suggest that trachoma does not meet the WHO definition of a public health problem in this Division of Fiji, but the inconsistency with previous studies warrants further investigation.

Azithromycin in control of trachoma

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