TPX2 Level Correlates with Hepatocellular Carcinoma Cell Proliferation, Apoptosis, and EMT

@article{Liang2015TPX2LC,
  title={TPX2 Level Correlates with Hepatocellular Carcinoma Cell Proliferation, Apoptosis, and EMT},
  author={Bo Liang and Chunhong Jia and Yu Huang and Hua He and Jialu Li and Hui Liao and Xiao Liu and Xincheng Liu and Xiaochun Bai and Dinghua Yang},
  journal={Digestive Diseases and Sciences},
  year={2015},
  volume={60},
  pages={2360-2372}
}
AbstractBackground Targeting protein for Xklp2 (TPX2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. TPX2 overexpression plays a key role in the progression of human cancers. But the underlying mechanism remains unclear. AimsThis study aimed to investigate the effects and mechanisms of TPX2 on the cell cycle, apoptosis, and epithelial–mesenchymal transition (EMT) in hepatocellular carcinoma (HCC).MethodsThe tissue TPX2 mRNA and protein were… CONTINUE READING

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