TP53 codon 72 polymorphism as a risk factor for cardiovascular disease in a Brazilian population.

@article{Smith2007TP53C7,
  title={TP53 codon 72 polymorphism as a risk factor for cardiovascular disease in a Brazilian population.},
  author={Marilia Cardoso Smith and M C Silva and Maysa Seabra Cendoroglo and Lucero Rengifo Ramos and Lara Miguel Quirino Ara{\'u}jo and Roger Willian de Labio and Rommel Rodr{\'i}guez Burbano and Elizabeth Suchi Chen and Spencer Luiz Marques Pay{\~a}o},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2007},
  volume={40 11},
  pages={
          1465-72
        }
}
TP53, a tumor suppressor gene, has a critical role in cell cycle, apoptosis and cell senescence and participates in many crucial physiological and pathological processes. Identification of TP53 polymorphism in older people and age-related diseases may provide an understanding of its physiology and pathophysiological role as well as risk factors for complex diseases. TP53 codon 72 (TP53:72) polymorphism was investigated in 383 individuals aged 66 to 97 years in a cohort from a Brazilian Elderly… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 38 REFERENCES

p53: guardian AND suppressor of longevity?

  • Experimental Gerontology
  • 2005
VIEW 1 EXCERPT