TP53 codon 72 polymorphism and colorectal cancer susceptibility: a meta-analysis

  title={TP53 codon 72 polymorphism and colorectal cancer susceptibility: a meta-analysis},
  author={Jing-jun Wang and Yuan Zheng and L. Sun and L. Wang and P. Yu and J. Dong and L. Zhang and J. Xu and W. Shi and Yu-Chun Ren},
  journal={Molecular Biology Reports},
  • Jing-jun Wang, Yuan Zheng, +7 authors Yu-Chun Ren
  • Published 2010
  • Medicine
  • Molecular Biology Reports
  • Colorectal cancer constitutes a significant proportion of the global burden of cancer morbidity and mortality. A number of studies have been conducted to explore whether TP53 codon 72 polymorphism is associated with colorectal cancer susceptibility. However, controversial results were obtained. In order to derive a more precise estimation of the relationship, we systematically searched Medline, Google scholar, and Ovid database for studies reported before May 2010. A total of 3603 colorectal… CONTINUE READING
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