• Corpus ID: 212588607

TOXIC EFFECT OF METHNOLIC EXTRACT OF HOUTTUYNIA CORDATA ON KIDNEY, BLOOD AND LIVER OF RATS

@inproceedings{Yadav2016TOXICEO,
  title={TOXIC EFFECT OF METHNOLIC EXTRACT OF HOUTTUYNIA CORDATA ON KIDNEY, BLOOD AND LIVER OF RATS},
  author={Sanjay Yadav and Sanjib K. Das and S. K. Ghosh and Hemant Kumar Nagar},
  year={2016}
}
The plant Houttuynia cordata Thunb (H. cordata) Family Saururuacea locally known as “Moshundari” is frequently used for medicinal and nutritional purpose in the Assam region of India. It is an erect, annual herbecious plant. It is posses variety of therapeutic and nutritional property such as antibacterial, anti-inflammatory, Anti allergic activity, Anticancer/Antitumor activity, Antidiabetic activity, Antioxidant activity, Antiviral activity, Immunomodulatory activity, Anti-obesity activity… 

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References

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The present review is an attempt to put an insight into a medicinal plant Houttuynia cordata Thunb, which is indigenous to North-East India and China, and describes therapeutic efficacy and various pharmacological activities reported on the plant.

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Houttuynia cordata Thunb. (H. cordata) is used as a remedy for diarrhoea and dysentery in Asia, but has not been investigated for its antidiarrhoeal properties. Antidiarrhoeal activity of 80%

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The collected information is an attempt to cover recent developments in the pharmacology, phytochemistry and quality control of H. cordata in order to confirm traditional wisdom in the light of a rational phytotherapy.

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The two fold broth dilution and agar dilution method were used to study essential oil of two Houttuynia THUNB.

Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity

Acute and Sub-Acute Toxicity Evaluation of the Methanolic Extract of Alstonia scholaris Stem Bark

The results demonstrate that, while a single dose and short term oral intake of Alstonia scholaris bark extract caused no toxicity up to a dose of 2000 mg/kg b.w., toxic effects manifested in the long term treatment at the highest dose (500 and 1000mg/kg); the long-term toxic effect was found to be associated with alterations in hematological compositions and end-organ damage to the liver.

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High-performance liquid chromatography analysis of H. cordata aqueous extract indicated that hyperoside was the predominant bioactive compound, and was likely to play a role in this inhibition of dengue virus, andHyperoside may be considered a lead compound possessing drug potential for further development.