TORCH test for fetal medicine indications: only CMV is necessary in the United Kingdom

  title={TORCH test for fetal medicine indications: only CMV is necessary in the United Kingdom},
  author={Sherif A. Abdel-Fattah and Abha Bhat and Sebastian Enrique Illanes and Jose Luis Bartha and David Carrington},
  journal={Prenatal Diagnosis},
To review the indications and value of TORCH testing (toxoplasma, rubella, cytomegalovirus, herpes) for fetal medicine reasons. 

A systematic review of maternal TORCH serology as a screen for suspected fetal infection

The acronym ‘TORCH’ refers to well‐recognised causes of perinatal infections: toxoplasmosis, rubella, cytomegalovirus (CMV) and herpes simplex virus (HSV). A TORCH serology panel is often used to

Prevalence of a positive TORCH and parvovirus B19 screening in pregnancies complicated by polyhydramnios

The aim of this study was to evaluate the rate of women with polyhydramnios who eventually screened positive to infectious disease by serum screening testing for TORCH and parvovirus B19.


A thesis submitted to the Department of Clinical Microbiology, Kwame Nkrumah University of Science and Technology, Kumasi in partial fulfilment of the requirements for the degree of Master of

Regression of fetal cerebral abnormalities by primary cytomegalovirus infection following hyperimmunoglobulin therapy

To assess the effects of maternal and intra‐amniotic hyperimmunoglobulin (HIG) infusions among cytomegalovirus (CMV) infected fetuses with ultrasound abnormalities following a primary CMV infection.

The utility of infection screening in isolated mild ventriculomegaly: an observational retrospective study on 141 fetuses

The aim of this study was to evaluate the utility of screening for infections in case of isolated mild ventriculomegaly (imVM) and to investigate the role of EMT in the selection of patients forimVM.

Recognizing TORCH Group of Infections on Fetal Sonography

The clinical features associated with TORCH with special emphasis on the in utero ultrasound-guided diagnosis of these infections in the fetus are summarized.

How to use...  neonatal TORCH testing

An overview of the pathogenesis, epidemiology and clinical consequences of congenital TORCH infections is provided and the indications for, and interpretation of, TORCH screens are discussed.

Is Routine TORCH Screening Warranted in Neonates with Lenticulostriate Vasculopathy?

Routine TORCH screening in neonates with LSV cases should only be regarded as mandatory once well-designed studies demonstrate a clear diagnostic benefit, and efforts to diagnose congenital infections in cases presenting with LSv have a poor yield.

Congenital Infections, Part I: Cytomegalovirus, Toxoplasma, Rubella, and Herpes Simplex

Information from recent studies is summarized to provide updates about the diagnostic and therapeutic strategies to combat this complex group of pathogens.

Impact of Syrian refugees on congenital TORCH infections screening in Turkey

The effect of the Syrian refugee population on the prevalence of congenital TORCH infections and the cost‐effectiveness of population‐based TORCH screening during pregnancy in Turkey are demonstrated.



Screening programme for congenital toxoplasmosis in France.

  • P. Thulliez
  • Medicine
    Scandinavian journal of infectious diseases. Supplementum
  • 1992
The high prevalence of Toxoplasma gondii infection in France led to the establishment of a national screening programme. Preventive measures were progressively introduced, and these became compulsory

Congenital cytomegalovirus infection: a dilemma.

Hence we still have no good evidence to suggest that we need to revise the safe daily drinking limits of 60 g ethanol for men and 30 g for women, though further longitudinal research is required to

Ultrasound and fetal diagnosis of perinatal infection.

  • J. Crino
  • Medicine
    Clinical obstetrics and gynecology
  • 1999
Fetal infection should be considered when multiple organ system anomalies, fetal growth restriction, placental enlargement, or abnormalities of amniotic fluid volume are demonstrated and the sonologist should understand the limitations of ultrasound.

Yield and costs of screening growth-retarded infants for torch infections.

The yield of workup for TORCH infection among infants with IUGR is poor and does not justify the incurred costs.

A prospective study of primary cytomegalovirus infection during pregnancy: final report

It is concluded that the lessons learned from studying rubella infection during pregnancy cannot be alied to cytomegalovirus; in particular, it is found no evidence that termination of pregnancy should be offered to women with early CMV infections.

Screening for toxoplasmosis during pregnancy.

It was not appropriate at the present time to introduce a nationwide antenatal screening programme for toxoplasmosis in the UK but the need for further research in this area was emphasised.

Diagnosis and treatment of herpes simplex infection during pregnancy.

  • D. Donahue
  • Medicine
    Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
  • 2002
Nurses delivering care to childbearing women and their newborns must be aware of the current information to give accurate and helpful information and support on women with primary infections, recurrent infections, and women at risk of acquiring the infection during pregnancy.

Prevalence of toxoplasma IgG among pregnant women in west London according to country of birth and ethnic group.

The seroprevalence of toxoplasma IgG is known to vary among countries,' but differences according to country of birth and ethnic group have not previously been investigated in a single population based study.

Lower-limb hypoplasia due to intrauterine infection with herpes simplex virus type 2: possible confusion with intrauterine varicella-zoster syndrome.

This is, to the best of the authors' knowledge, the first case of a patient with in utero-acquired HSV-2 infection presenting with a limb hypoplasia, and illustrates that, in addition to congenital varicella-zoster syndrome, HSV -2 infection should also be considered in patients presenting with limb Hypoplasia.