TORC1 of fission yeast is rapamycin-sensitive.

  title={TORC1 of fission yeast is rapamycin-sensitive.},
  author={Terunao Takahara and Tatsuya Maeda},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  volume={17 8},
The target of rapamycin (TOR) protein kinase plays central roles in the regulation of cell growth in response to nutritional availability. TOR forms two distinct multiprotein complexes termed TOR complex 1 (TORC1) and TORC2. Typically, only the activity of TORC1 is inhibited by the immunosuppressant rapamycin. Although rapamycin strongly inhibits cell growth of the budding yeast Saccharomyces cerevisiae through inhibition of TORC1, growth of the fission yeast Schizosaccharomyces pombe appears… CONTINUE READING

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