TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases


The coupling of growth to cell cycle progression allows eukaryotic cells to divide at particular sizes depending on nutrient availability. In fission yeast, this coupling involves the Spc1/Sty1 mitogen-activated protein kinase (MAPK) pathway working through Polo kinase recruitment to the spindle pole bodies (SPBs). Here we report that changes in nutrients… (More)
DOI: 10.1038/ncb1646


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