TOPLESS co-repressor interactions and their evolutionary conservation in plants

@inproceedings{Causier2012TOPLESSCI,
  title={TOPLESS co-repressor interactions and their evolutionary conservation in plants},
  author={Barry Causier and James B. Lloyd and Laura Stevens and Brendan H Davies},
  booktitle={Plant signaling & behavior},
  year={2012}
}
Large-scale protein-protein interaction studies recently demonstrated that the Arabidopsis TPL/TPR family of transcriptional co-repressors is involved in a broad range of developmental processes. TPL/TPRs predominantly interact with transcription factors that contain repression domain (RD) sequences. Interestingly, RDs reported in the literature are quite diverse in sequence, yet TPL/TPRs interact with proteins containing all of the known motifs. These data lead us to conclude that the TPL/TPRs… CONTINUE READING

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