TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies.

@article{Zapata2000TNFRassociatedFF,
  title={TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies.},
  author={Juan Marcelo Zapata and Maryla Krajewska and Stan Stanislaw Krajewski and Shinichi Kitada and Ken Ian Welsh and Anne P Monks and Natalie McCloskey and John Gordon and Thomas J. Kipps and Randy D. Gascoyne and A. Shabaik and John C. Reed},
  journal={Journal of immunology},
  year={2000},
  volume={165 9},
  pages={5084-96}
}
TNFR-associated factors (TRAFs) constitute a family of adapter proteins that associate with particular TNF family receptors. Humans and mice contain six TRAF genes, but little is known about their in vivo expression at the single cell level. The in vivo locations of TRAF1, TRAF2, TRAF5, and TRAF6 were determined in human and mouse tissues by immunohistochemistry. Striking diversity was observed in the patterns of immunostaining obtained for each TRAF family protein, suggesting their expression… CONTINUE READING