TNF-related apoptosis-inducing ligand suppresses PRDX4 expression.

Abstract

TNF-related apoptosis-inducing ligand (TRAIL) is currently considered a promising target for developing anti-cancer therapies. Accumulating evidences have now shown that oxidative stress is involved in the TRAIL-mediated cell death. The peroxiredoxins (PRDXs) are a ubiquitous family of proteins involved in protection against oxidative stress through the… (More)
DOI: 10.1016/j.febslet.2009.04.009

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