TNF polymorphisms and prostate cancer risk.

  title={TNF polymorphisms and prostate cancer risk.},
  author={Kim N. Danforth and C. D{\'i}az Rodr{\'i}guez and Richard B Hayes and Lori C. Sakoda and Wen-Yi Huang and Kai Yu and Eugenia E. Calle and Eric J Jacobs and Bingshu E. Chen and Gerald L. Andriole and Jonine D Figueroa and Meredith Yeager and Elizabeth A. Platz and Dominique S. Michaud and Stephen J. Chanock and Michael J. Thun and Ann W Hsing},
  journal={The Prostate},
  volume={68 4},
BACKGROUND Inflammation has been hypothesized to increase prostate cancer risk. Tumor necrosis factor (TNF) is an important mediator of the inflammatory process, but the relationship between TNF variants and prostate cancer remains unclear. METHODS We examined associations between six TNF single nucleotide polymorphisms (SNPs) (rs1799964, rs1800630, rs1799724, rs1800629, rs361525, rs1800610) and prostate cancer risk among 2,321 cases and 2,560 controls from two nested case-control studies… CONTINUE READING