TNF-α inhibitory diterpenoids from the Chinese mangrove plant Excoecaria agallocha L.

@article{Li2010TNFID,
  title={TNF-α inhibitory diterpenoids from the Chinese mangrove plant Excoecaria agallocha L.},
  author={Yongxin Li and Jun Yong Liu and Shanjiang Yu and Peter Proksch and Jun Gu and Wenhan Lin},
  journal={Phytochemistry},
  year={2010},
  volume={71 17-18},
  pages={2124-31}
}
Chemical examination of the stems and twigs of the mangrove plant Excoecaria agallocha L. resulted in the isolation of six ent-kaurane diterpenoids named agallochaols K-P (1-6), an atisane-type diterpenoid agallochaol Q (7), along with eight known diterpenoids (8-15). Their structures were elucidated on the basis of extensive spectroscopic analysis and by comparison of their NMR spectroscopic data with those reported in literature, in association with the biogenetic relationship with the X-ray… CONTINUE READING