TNF-α Blocker Effect of Naringenin-Loaded Sericin Microparticles that Are Potentially Useful in the Treatment of Psoriasis

@inproceedings{Chlapanidas2014TNFBE,
  title={TNF-α Blocker Effect of Naringenin-Loaded Sericin Microparticles that Are Potentially Useful in the Treatment of Psoriasis},
  author={Theodora Chlapanidas and Sara Perteghella and Flavio Leoni and Silvio Farag{\`o} and Mario Marazzi and Daniela Rossi and Emanuela Martino and Raffaella Gaggeri and Simona Collina},
  booktitle={International journal of molecular sciences},
  year={2014}
}
This study aims to evaluate the effect of combined use of the racemic flavanone Naringenin (NRG) and the protein sericin as TNF-α blockers. Sericin (SMs) and (R/S) NRG-loaded Sericin (SNRGMs) microparticles were prepared by spray-drying, characterized in terms of morphology and particle size distribution, and encapsulation efficiency was determined. Concerning morphology and particle size distribution of microparticles, results indicated that they were not affected by the presence of NRG. The… CONTINUE READING
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