TNFα- and IL-17A-mediated S100A8 expression is regulated by p38 MAPK.

@article{Mose2013TNFAI,
  title={TNFα- and IL-17A-mediated S100A8 expression is regulated by p38 MAPK.},
  author={Maike Mose and Zhanyuan Kang and Line Raaby and Lars Iversen and Claus Johansen},
  journal={Experimental dermatology},
  year={2013},
  volume={22 7},
  pages={476-81}
}
The antimicrobial peptide S100A8 is known to be upregulated in lesional psoriatic skin compared with non-lesional psoriatic skin and is believed to play a role in the pathogenesis of psoriasis. However, little is known about the signalling pathways involved in the regulation of S100A8 expression. Using quantitative real-time RT-PCR analysis, we demonstrated… CONTINUE READING