TNFα-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2+ neutrophils

@inproceedings{Yu2017TNFactivatedMS,
  title={TNFα-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2+ neutrophils},
  author={Pengfei Yu and Yin Huang and Yuxuan Han and Liangyu Lin and Weihong Sun and Arnold B. Rabson and Y Wang and Yufang Shi},
  booktitle={Oncogene},
  year={2017}
}
Mesenchymal stromal cells (MSCs) tend to infiltrate into tumors and form a major component of the tumor microenvironment. Our previous work demonstrated that tumor necrosis factor α (TNFα)-activated MSCs significantly promoted tumor growth. However, the role of TNFα-treated MSCs in tumor metastasis remains elusive. Employing a lung metastasis model of… CONTINUE READING