TNF, IL-1, IL-6, IL-8 and soluble TNF receptors in relation to chorioamnionitis and premature labor.

@article{Arntzen1998TNFII,
  title={TNF, IL-1, IL-6, IL-8 and soluble TNF receptors in relation to chorioamnionitis and premature labor.},
  author={K J Arntzen and A M Kj\ollesdal and Jostein Halgunset and Lars J Vatten and Rigmor Austgulen},
  journal={Journal of perinatal medicine},
  year={1998},
  volume={26 1},
  pages={17-26}
}
Inflammatory cytokines seem to play a key role in mechanisms initiating labor. Since cytokine levels are higher in preterm than in term labor, it has been hypothesized that labor-inducing effects of cytokines are inhibited by an upregulated production of cytokine antagonists, such as soluble cytokine receptors, at early stages of gestation. In this study, TNF, IL-1, IL-6, IL-8 and soluble TNF receptors (sTNFRs) were measured in amniotic fluid samples from a) 39 women in premature labor, b) 25… CONTINUE READING