TMEM16A alternative splicing coordination in breast cancer

  title={TMEM16A alternative splicing coordination in breast cancer},
  author={Ifeoma Ubby and Erica Bussani and Antonio Colonna and Giuseppe Stacul and Martina Locatelli and Paolo Scudieri and Luis J. V. Galietta and Franco Pagani},
  booktitle={Molecular Cancer},
TMEM16A, also known as Anoctamin-1, is a calcium-activated chloride channel gene overexpressed in many tumors. The role of TMEM16A in cancer is not completely understood and no data are available regarding the potential tumorigenic properties of the multiple isoforms generated by alternative splicing (AS). We evaluated TMEM16A AS pattern, isoforms distribution and Splicing Coordination (SC), in normal tissues and breast cancers, through a semi-quantitative PCR-assay that amplifies transcripts… CONTINUE READING
Highly Cited
This paper has 24 citations. REVIEW CITATIONS
13 Citations
50 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 13 extracted citations


Publications referenced by this paper.
Showing 1-10 of 50 references

Similar Papers

Loading similar papers…