TMEM119 marks a subset of microglia in the human brain.

  title={TMEM119 marks a subset of microglia in the human brain.},
  author={Jun-ichi Satoh and Yoshihiro Kino and Naohiro Asahina and Mika Takitani and Junko Miyoshi and Tsuyoshi Ishida and Yuko Saito},
  journal={Neuropathology : official journal of the Japanese Society of Neuropathology},
  volume={36 1},
Microglia are resident myeloid cells of the central nervous system (CNS), activated in the brains of various neurological diseases. Microglia are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. However, a lack of specific markers that distinguish resident microglia from circulating blood-derived macrophages in human brain tissues hampers accurate evaluation of microglial contributions to the human brain pathology… CONTINUE READING