TLR9 turns the tide on Treg cells.

@article{Mills2008TLR9TT,
  title={TLR9 turns the tide on Treg cells.},
  author={Kingston H G Mills},
  journal={Immunity},
  year={2008},
  volume={29 4},
  pages={518-20}
}
In this issue of Immunity, Hall et al. (2008) demonstrate that commensal bacterial DNA can suppress Treg cell conversion via TLR9-mediated activation of lamina propria dendritic cells and thus potentially disrupt intestinal homeostasis.