TLR9 ligand enhances proliferation of rat CD4+ T cell and modulates suppressive activity mediated by CD4+ CD25+ T cell.

@article{Chiffoleau2007TLR9LE,
  title={TLR9 ligand enhances proliferation of rat CD4+ T cell and modulates suppressive activity mediated by CD4+ CD25+ T cell.},
  author={Elise Chiffoleau and Jean-Marie Heslan and Mich{\`e}le Heslan and C{\'e}dric Louvet and Thomas Condamine and Maria-Cristina Cuturi},
  journal={International immunology},
  year={2007},
  volume={19 2},
  pages={193-201}
}
Toll-like receptors (TLRs) play a crucial role in the initiation of innate responses following microbial infection and also in adaptive immune responses by orchestrating the activation of different cell populations. TLRs are expressed at high levels in antigen-presenting cells and recent studies have demonstrated the expression and biological role of TLRs in mouse and human CD4(+) T cells. In this study, we analyzed TLR mRNA expression in rat CD4(+) T cells using stringent quantitative reverse… CONTINUE READING