TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival

@inproceedings{Menino2013TLR9AD,
  title={TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival},
  author={Jo{\~a}o Filipe Menino and Margarida Saraiva and Ana G Gomes-Alves and Diogo Lobo-Silva and Mark H. J. Sturme and J{\'e}ssica Gomes-Rezende and Ana Laura Saraiva and Gustavo Henrique Goldman and C Amila P. Cunha and Agostinho Carvalho and Luigina Romani and Jorge Pedrosa and Ant{\'o}nio Gil Castro and Fernando Rodrigues},
  booktitle={PLoS neglected tropical diseases},
  year={2013}
}
BACKGROUND Paracoccidioides brasiliensis causes paracoccidioidomycosis, one of the most prevalent systemic mycosis in Latin America. Thus, understanding the characteristics of the protective immune response to P. brasiliensis is of interest, as it may reveal targets for disease control. The initiation of the immune response relies on the activation of pattern recognition receptors, among which are TLRs. Both TLR2 and TLR4 have been implicated in the recognition of P. brasiliensis and regulation… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 74 REFERENCES

Paracoccidioidomycosis: an update.

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL