TLR5 mediates CD172α+ intestinal lamina propria dendritic cell induction of Th17 cells

@inproceedings{Liu2016TLR5MC,
  title={TLR5 mediates CD172α+ intestinal lamina propria dendritic cell induction of Th17 cells},
  author={Han Liu and Feidi Chen and Wei Wu and Anthony T. Cao and Xiaochang Xue and Suxia Yao and Heather L. Evans-Marin and Yan-Qing Li and Yingzi Cong},
  booktitle={Scientific reports},
  year={2016}
}
Multiple mechanisms exist in regulation of host responses to massive challenges from microbiota to maintain immune homeostasis in the intestines. Among these is the enriched Th17 cells in the intestines, which regulates intestinal homeostasis through induction of antimicrobial peptides and secretory IgA among others. However, the means by which Th17 cells develop in response to microbiota is still not completely understood. Although both TLR5 and CD172α(+) lamina propria dendritic cells (LPDC… CONTINUE READING