TLR4 signaling promotes the expression of VEGF and TGFbeta1 in human prostate epithelial PC3 cells induced by lipopolysaccharide.

@article{Pei2008TLR4SP,
  title={TLR4 signaling promotes the expression of VEGF and TGFbeta1 in human prostate epithelial PC3 cells induced by lipopolysaccharide.},
  author={Zengyang Pei and Degui Lin and Xiaoyu Song and Hui Li and Haifeng Yao},
  journal={Cellular immunology},
  year={2008},
  volume={254 1},
  pages={20-7}
}
Chronic inflammation promotes tumor development and progression, and Toll-like receptors (TLRs) may play an important role in this process. In this study, we found that human prostate epithelial PC3 cells constitutively express TLR4 in mRNA and protein level. lipopolysaccharide (LPS) promotes the expression and secretion of immunosuppressive cytokine… CONTINUE READING