TLR3 expression correlates with apoptosis, proliferation and angiogenesis in hepatocellular carcinoma and predicts prognosis

@inproceedings{Yuan2015TLR3EC,
  title={TLR3 expression correlates with apoptosis, proliferation and angiogenesis in hepatocellular carcinoma and predicts prognosis},
  author={Ming-Ming Yuan and Yu-yin Xu and Li Chen and Xing-Yu Li and Jing Qin and Ying Shen},
  booktitle={BMC Cancer},
  year={2015}
}
Toll-like receptor 3 (TLR3) plays a key role in innate immunity. In the present study, we analyzed tissues of patients with human hepatocellular carcinoma (HCC) to determine the significance of the relationship between TLR3 expression and cell proliferation, apoptosis, hepatitis B virus infections, angiogenesis and prognosis. We collected paraffin-embedded tissues from 85 patients with HCC who had complete histories and were followed for >5 years. The expression and intracellular localization… CONTINUE READING
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