TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence.

Abstract

Primary ovarian cancer is responsive to treatment, but chemoresistant recurrent disease ensues in majority of patients. Recent compelling evidence demonstrates that a specific population of cancer cells, the cancer stem cells, initiates and sustains tumors. It is therefore possible that this cell population is also responsible for recurrence. We have shown… (More)
DOI: 10.4161/cc.23406

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