TLR2 and TLR4 expression on CD14(++) and CD14(+) monocyte subtypes in adult-onset autoimmune diabetes.

@article{ejkov2016TLR2AT,
  title={TLR2 and TLR4 expression on CD14(++) and CD14(+) monocyte subtypes in adult-onset autoimmune diabetes.},
  author={Pavl{\'i}na {\vC}ejkov{\'a} and Iva Nemeckova and Jan Bro{\vz} and M Cerna},
  journal={Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia},
  year={2016},
  volume={160 1},
  pages={76-83}
}
BACKGROUND Peripheral blood monocytes are key effectors of innate immunity. Dysfunction, changes in their counts or altered expression of cytokines and pattern-recognition receptors on monocytes may contribute to the development of the autoimmune type of diabetes mellitus (AD). AIMS We aimed to analyze the counts and proportions of the two main subtypes of monocyte cells, CD14(++) and CD14(+), and to look for potential changes in the expression of toll-like receptors 2 (TLR2) and 4 (TLR4) as… CONTINUE READING
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