TLR stimulation of prostate tumor cells induces chemokine-mediated recruitment of specific immune cell types.

@article{Galli2010TLRSO,
  title={TLR stimulation of prostate tumor cells induces chemokine-mediated recruitment of specific immune cell types.},
  author={Roberta Galli and Donatella Starace and Roberta Bus{\`a} and Daniela Francesca Angelini and A. Paone and Paola de Cesaris and Antonio Filippini and Claudio Sette and Luca Battistini and Elio Ziparo and Anna Riccioli},
  journal={Journal of immunology},
  year={2010},
  volume={184 12},
  pages={
          6658-69
        }
}
TLRs boost antimicrobial response mechanisms by epithelial cells and represent the first line of defense at mucosal sites. In view of these immunomodulatory properties, TLR stimulation may represent a novel means to activate anticancer immune responses. In the present study, the ability of TLR ligands to affect the recruitment of different immune cell populations by human prostate cancer cell lines and the underlying mechanisms were investigated. We showed that LNCaP and DU-145 cells express… CONTINUE READING
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