TLR Agonists as Modulators of the Innate Immune Response and Their Potential as Agents Against Infectious Disease

@inproceedings{Mifsud2014TLRAA,
  title={TLR Agonists as Modulators of the Innate Immune Response and Their Potential as Agents Against Infectious Disease},
  author={Edin Jessica Mifsud and Amabel C. L. Tan and David C Jackson},
  booktitle={Front. Immunol.},
  year={2014}
}
Immunotherapies that can either activate or suppress innate immune responses are being investigated as treatments against infectious diseases and the pathology they can cause. The objective of these therapies is to elicit protective immune responses thereby limiting the harm inflicted by the pathogen. The Toll-like receptor (TLR) signaling pathway plays critical roles in numerous host immune defenses and has been identified as an immunotherapeutic target against the consequences of infectious… CONTINUE READING
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