TLR-2, TLR-4 and dectin-1 expression in human monocytes and neutrophils stimulated by Paracoccidioides brasiliensis.

@article{Bonfim2009TLR2TA,
  title={TLR-2, TLR-4 and dectin-1 expression in human monocytes and neutrophils stimulated by Paracoccidioides brasiliensis.},
  author={Camila Vicente Bonfim and Ronei Luciano Mamoni and Maria Heloisa Souza Lima Blotta},
  journal={Medical mycology},
  year={2009},
  volume={47 7},
  pages={
          722-33
        }
}
Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin America caused by the dimorphic fungus Paracoccidioides brasiliensis. The pattern of the immune responses to P. brasiliensis determines the disease progression and clinical outcome. Innate immune response is mediated by phagocytic cells, such as macrophage and neutrophils, which ingest and kill invading pathogens and then trigger the adaptive immune system through the secretion of cytokines and chemokines. The C-type like lectin… CONTINUE READING
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