TIP60-miR-22 axis as a prognostic marker of breast cancer progression.

Abstract

MicroRNAs (miRNAs) are 22- to 24-nucleotide, small, non-coding RNAs that bind to the 3'UTR of target genes to control gene expression. Consequently, their dysregulation contributes to many diseases, including diabetes and cancer. miR-22 is up-regulated in numerous metastatic cancers and recent studies have suggested a role for miR-22 in promoting stemness… (More)
DOI: 10.18632/oncotarget.5636

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