THU0021 Differential effects of tr14 versus diclofenac on cox/lox pathways revealed by rnaseq

@article{Laurent2018THU0021DE,
  title={THU0021 Differential effects of tr14 versus diclofenac on cox/lox pathways revealed by rnaseq},
  author={G. St. Laurent and I. Toma and B. Seilheimer and M. Tackett and J. Zhou and M. Ri and D. Shtokalo and Y. Vyatkin and T. Jepson and K. Cesnulevicius and T. Mccaffrey},
  journal={Annals of the Rheumatic Diseases},
  year={2018},
  volume={77},
  pages={238 - 239}
}
Background Anti-inflammatory agents are used widely in treating numerous pain and inflammatory conditions. With a focus on the COX/LOX pathways in cutaneous wound repair in mice, the therapeutic activities of Tr14 (Traumeel), a multicomponent/multitarget natural product, and diclofenac (NSAID), a non-selective cyclooxygenase (COX) inhibitor were compared. The COX enzymes convert arachidonic acid into prostaglandins and thromboxanes, while the lipoxygenase (LOX) pathway generates more pro… Expand