THP-1 Macrophages and SGBS Adipocytes – A New Human in vitro Model System of Inflamed Adipose Tissue

Abstract

Obesity is associated with an accumulation of macrophages in adipose tissue. This inflammation of adipose tissue is a key event in the pathogenesis of several obesity-related disorders, particularly insulin resistance. Here, we summarized existing model systems that mimic the situation of inflamed adipose tissue in vitro, most of them being murine… (More)
DOI: 10.3389/fendo.2011.00089

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@inproceedings{Keuper2011THP1MA, title={THP-1 Macrophages and SGBS Adipocytes – A New Human in vitro Model System of Inflamed Adipose Tissue}, author={Michaela Keuper and Anna A. Dzyakanchuk and Kurt E. Amrein and Martin Wabitsch and Pamela Fischer-Posovszky}, booktitle={Front. Endocrin.}, year={2011} }