THE SUPPRESSION OF NK ACTIVITY BY THE CHEMICAL CARCINOGEN DIMETHYLBENZANTHRACENE AND ITS RESTORATION BY INTERFERON OR POLY I:C

@inproceedings{Ehrlich1982THESO,
  title={THE SUPPRESSION OF NK ACTIVITY BY THE CHEMICAL CARCINOGEN DIMETHYLBENZANTHRACENE AND ITS RESTORATION BY INTERFERON OR POLY I:C},
  author={Rachel Ehrlich and Elinor Malatzky and Margalit Efrati and Isaac P. Witz},
  year={1982}
}
Publisher Summary This chapter examines suppression of natural killer (NK) activity by the chemical carcinogen dimethylbenzanthracene (DBMA) and its restoration by interferon or poly I:C. In a study described in the chapter, normal BALB/c mice or pituitary isografted mice were fed with DMBA. Tumor incidence was 60% in the former and about 100% in the latter group. Untreated mice that were only given a pituitary isograft did not develop tumors. Mice belonging to these four groups were inspected… CONTINUE READING