THE SIGNIFICANCE OF THE NITROGLYCERINE FLICKER FUSION RESPONSE IN NORMAL SUBJECTS AND IN PREGNANCY

@article{Morris1953THESO,
  title={THE SIGNIFICANCE OF THE NITROGLYCERINE FLICKER FUSION RESPONSE IN NORMAL SUBJECTS AND IN PREGNANCY},
  author={Nicholas Morris and John S. Tomkinson and B J O'Connor},
  journal={BJOG: An International Journal of Obstetrics \& Gynaecology},
  year={1953},
  volume={60}
}
THE nitroglycerine flicker fusion reaction has been used in an attempt to diagnose latent preeclampsia. The Flicker Fusion Threshold (F.F.T.) can be defined as the minimal number of successive flashes of light at which the light stimulus appears to be continuous and free from flicker. This test has been used by visual physiologists for well over a century but only in recent years has the technique been adopted for clinical investigation. In 1950 Krasno and Ivy described a relatively simple… 
5 Citations
Flicker photometry and toxemia of pregnancy.
  • F. Perl, A. Oper
  • Medicine
    American journal of obstetrics and gynecology
  • 1956
Critical flicker frequency, photochemical mechanisms, and perceptual responses.
TLDR
The meaningfulness of the flicker phenomenon is directed to, as shown in its correlation with electroretinography, and the need of applying psychometric principles in ophthalmic practice is demonstrated, by referring to laboratory results.
A STATISTICAL EVALUATION OF THE NITROGLYCERINE FLICKER‐FUSION THRESHOLD TEST AND THE “WEIGHT‐GAIN SIGN” IN THE PREDICTION OF THE CLINICAL SYNDROME OF PRE‐ECLAMPSIA
TLDR
Test the prognostic significance attributed to the Nitroglycerine FlickerFusion Threshold Test by Brill and to excessive 20-30 week primigravid weight-gain by Hamlin in pre-eclampsia to fit them into the scheme of a large-scale enquiry into the aetiology and management of toxaemia.

References

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The Response of the Flicker Fusion Threshold to Nitroglycerin and Its Potential Value in the Diagnosis, Prognosis, and Therapy of Subclinical and Clinical Cardiovascular Disease
TLDR
It is suggested that this test may be of use in the diagnosis of equivocal cases and for the evaluation of therapeutic measures.
The Flicker Fusion Frequency and Its Response to Nitroglycerin in Normal Subjects and in Patients with Cardiovascular Disease
TLDR
Claims that the change after sublingual nitroglycerin in the frequency at which a flickering light appears to fuse sharply differentiates between cardiovascular normals and patients with coronary and/or hypertensive disease are denied.
Flicker fusion thresholds in pregnancy.
The preclinical recognition of toxemia of pregnancy.
The Nitroglycerin‐Flicker Test
TLDR
It is concluded that the use of the nitroglycerin-flicker test in mass surveys to detect cardiovascular disease is not justified.