THE RÔLE OF THE COMPONENTS OF COMPLEMENT IN SPECIFIC IMMUNE FIXATION

@article{Pillemer1942THERO,
  title={THE R{\^O}LE OF THE COMPONENTS OF COMPLEMENT IN SPECIFIC IMMUNE FIXATION},
  author={Louis Pillemer and Sam Seifter and E. E. Ecker},
  journal={The Journal of Experimental Medicine},
  year={1942},
  volume={75},
  pages={421 - 435}
}
From the experiments reported here it is evident that the amount of each complement component which combines with specific immune aggregates depends upon a number of factors, including the age of the complement; the concentrations of antigen, antibody, and complement; hydrogen ion and electrolyte concentrations; and time and temperature of incubation for fixation. The experiments also reveal the following: 1. C'4 must be considered a combining component of complement because it is invariably… CONTINUE READING

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