THE OXYTOCIC EFFECT OF ACRIDINE DYES AND THEIR USE IN TERMINATING MID‐TRIMESTER PREGNANCIES

@article{Lewis1971THEOE,
  title={THE OXYTOCIC EFFECT OF ACRIDINE DYES AND THEIR USE IN TERMINATING MID‐TRIMESTER PREGNANCIES},
  author={B. Lewis and A. Pybus and J. Stilwell},
  journal={BJOG: An International Journal of Obstetrics \& Gynaecology},
  year={1971},
  volume={78}
}
The oxytocic effect of an acridine dye, aminacrine hydrochloride, has been investigated on isolated strips of myometrium from pregnant and non‐pregnant human uteri. Contractions were induced when the muscle strips were perfused with an aqueous solution of aminacrine at a concentration of 10–5–10–4M. 50 ml. of an 0.1 per cent solution of aminacrine was introduced into the extra‐amniotic space in 23 women in order to induce therapeutic abortion in the mid‐trimester. All the patients aborted after… Expand
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