THE ORNITHINE CYCLE IN NEUROSPORA AND ITS GENETIC CONTROL

@article{Srb1944THEOC,
  title={THE ORNITHINE CYCLE IN NEUROSPORA AND ITS GENETIC CONTROL},
  author={Adrian M. Srb and Norman H. Horowitz},
  journal={Journal of Biological Chemistry},
  year={1944},
  volume={154},
  pages={129-139}
}
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Biochemical genetics of Neurospora.

Genetics of arginine biosynthesis in Neurospora crassa.

A large number of arginine-requiring mutants of Neurospora was isolated, using a strain already partially impaired in an enzyme of the pathway, and several new loci were defined and mapped, suggesting a bifunctional gene, possibly controlling two steps in ornithine synthesis.

The use of mutants in the study of metabolism

It will be shown that methods contributed by the field of biochemical genetics lead to conclusions that are consistent with, and complementary to, those derived from isotope and enzyme studies.

Genetic control of aspartate transcarbamylase by the pyr-3 locus of Neurospora crassa.

Genetics and biochemistry of morphogenesis in Neurospora.

Arginine synthesis in Neurospora crassa; Genetic studies.

Nine mutants of Neurospora crassa which require arginine as a nutrient but cannot use citrulline were obtained from various sources and it was concluded that the high arg + frequency is due to selection, and that the mutants might be pseudoalleles.

Genetic studies of mutants of Neurospora crassa lacking ornithine transcarbamylase

Arginine has long been of interest to chemists, biochemists and biologists because of its close relation¬ ship to urea and there were indications that arginine biosynthesis was more complex than originally believed.

Enzymes of Deamination, Decarboxylation, Transmethylation and Intermediary Metabolism

From the viewpoint of comparative biochemistry it would, for instance, be interesting to know the nature of the enzyme synthesizing carbamyl phosphate in higher plants and fungi.

Genetics and molecular biology of Neurospora crassa.

Arginine Synthesis in Neurospora crassa

Nine mutants of Neurospora crassa which require arginine as a nutrient but cannot use citrulline were obtained and it was concluded that the high arg+ frequency is due to selection, and that the mutants might be pseudoalleles.
...

References

SHOWING 1-6 OF 6 REFERENCES

Perspectives in Biochemistry

  • C. Long
  • Education
    The Yale Journal of Biology and Medicine
  • 1938
PERSPECTIVES IN BIOCHEMISTRY: Thirty-one essays presented to Sir Frederick Gowland Hopkins by past and present members of his laboratory. Edited by Joseph Needham and David E. Green. Cambridge…

Annual Review of Biochemistry

In his story of his visit to India, Prof. A. V. Hill has emphasized the need for biological research in particular in order to solve the many complex Indian problems.

The Inborn Factors In Disease

Proc. Nut. Acad. SC

  • Proc. Nut. Acad. SC
  • 1941

Biochem. J

  • Biochem. J
  • 1941

J. Biol. Chem

  • J. Biol. Chem
  • 1943