THE NATURE OF THE VIRUS OF EPIDEMIC POLIOMYELITIS

@article{FlexnerTHENO,
  title={THE NATURE OF THE VIRUS OF EPIDEMIC POLIOMYELITIS},
  author={Simon Flexner and Paul A. Lewis},
  journal={JAMA},
  pages={2095-2095}
}
In our previous articles 1 on the transmission of epidemic poliomyelitis to monkeys, we have left undiscussed the nature of the virus responsible for producing the disease. Prom the beginning, our attention has been directed toward the solution of that fundamental question, but the results of our studies were, until recently, wholly of a negative nature. We failed utterly to discover bacteria, either in film preparations or in cultures, that could account for the disease; and, since among our… 
THE ETIOLOGY OF EPIDEMIC POLIOMYELITIS: PRELIMINARY NOTE
After Landsteiner and Levaditi 1 and Flexner and Lewis 2 demonstrated independently that the causative agent of epidemic poliomyelitis could be passed through a bacterial filter, the disease was
A CONTRIBUTION TO THE BACTERIOLOGY OF ACUTE A N T E R I O R POLIOMYELITIS.*
TLDR
The purpose of this communication is to present the results of the work with many different cultures of these easily cultivated bacteria isolated from persons ill with acute anterior poliomyelitis.
POLIOMYELITIS: I. EXPERIMENTAL AND THEORETICAL BASIS FOR SERUM THERAPY; A REVIEW
TLDR
In part II the experiences of all the investigators who have attempted to treat poliomyelitis in the acute stage by serums and other measures are reviewed, and it is pointed out that when these previous reports are compared with observations on the average natural trend of the disease, additional doubt is being cast on the practical value of this and other types of serum.
A history of viral infections of the central nervous system: foundations, milestones, and patterns.
VIRUS of poliomyelitis.
  • S. Gard
  • Medicine
    Bulletin of the U.S. Army Medical Department. United States. Army. Medical Department
  • 1945
In 1908 Landsteiner reported the first successful transmission of human poliomyelitis to monkeys. His observation was readily confirmed by i. a. Flexner and Lewis (1909a) and Leiner and von Wiesner
CHEMOPROPHYLAXIS AGAINST IMPENDING POLIOMYELITIS
TLDR
While this paper deals primarily with the application of chemicals to the olfactory nerves as a preventive measure against the disease, it is of interest to review some of the history and the experimental data which may lead to success in this method of prophylactic treatment.
VI. The Tonsils as an Atrium of Infection in Poliomyelitis
TLDR
Anterior poliomyelitis is an infectious disease accompanied in a certain proportion of cases by paralysis, but the percentage of cases in which paralysis occurs is a great deal lower than has been previously believed-perhaps one in four.
A CONTRIBUTION TO THE BACTERIOLOGY OF ACUTE ANTERIOR POLIOMYELITIS
Four different varieties of easily cultivated microorganisms have been cultured from the cerebrospinal fluid and tissues of cases of acute anterior poliomyelitis; namely, a streptococcus, a
Peyton Rous: A Centennial Tribute to the Founding Father of Cancer Virology
TLDR
New studies are reported on showing how Warthin and Schmorl strengthened the advancement of Rous by ensuring his sound grounding in pathology, particularly in the fields of viral oncology and blood preservation.
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References

The Transmission of Acute Poliomyelitis to Monkeys
TLDR
Poliomyelitis or infantile paralysis prevailed in epidemic form along the Atlantic seaboard in the summer of 1907 and reappeared as a focalized epidemic in Greater New York and had, by that time, spread widely throughout the United States and Europe.